Spebrutinib (CC-292, AVL-292)

Spebrutinib (CC-292, AVL-292)

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Spebrutinib (CC-292, AVL-292) is a covalent, orally active, and highly selective BTK inhibitor with IC50 of <0.5 nM, displaying at least 1400-fold selectivity over the other kinases assayed. Phase 1.

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