PKI-402

PKI-402

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PKI-402 is a potent dual pan-PI3K/mTOR inhibitor targeting PI3K?/?/?/? and mTOR with IC50 of 2 nM/7 nM/16 nM/14 nM and 3 nM, respectively; also potent to PI3K? mutants E545K and H1047R.

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