Omipalisib (GSK2126458, GSK458) is a highly selective and potent inhibitor of p110?/?/?/?, mTORC1/2 with Ki of 0.019 nM/0.13 nM/0.024 nM/0.06 nM and 0.18 nM/0.3 nM in cell-free assays, respectively. Phase 1.
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