Sonidegib (Erismodegib, NVP-LDE225)

Sonidegib (Erismodegib, NVP-LDE225)

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Sonidegib (Erismodegib, NVP-LDE225) is a Smoothened (Smo) antagonist, inhibiting Hedgehog (Hh) signaling with IC50 of 1.3 nM (mouse) and 2.5 nM (human) in cell-free assays, respectively. Phase 3.

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