KRN 633

KRN 633

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KRN 633 is an ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 170 nM/160 nM/125 nM, weakly inhibits PDGFR-?/? and c-Kit, does not block the phosphorylation of FGFR-1, EGFR or c-Met in cell.

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