LY2811376

LY2811376

  • $320.00
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LY2811376 is the first orally available non-peptidic ?-secretase(BACE1) inhibitor with IC50 of 239 nM-249 nM, that act to decrease A? secretion with EC50 of 300 nM, demonstrated to have 10-fold selectivity towards BACE1 over BACE2, and more than 50-fold inhibition over other aspartic proteases including cathepsin D, pepsin, or renin. Phase 1.

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