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Staurosporine is a potent PKC inhibitor for PKC?, PKC? and PKC? with IC50 of 2 nM, 5 nM and 4 nM, less potent to PKC? (20 nM), PKC? (73 nM) and little active to PKC? (1086 nM) in cell-free assays. Also shows inhibitory activities on other kinases, such as PKA, PKG, S6K, CaMKII, etc. Phase 3.