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CHIR-99021 (CT99021)

CHIR-99021 (CT99021)

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CHIR-99021 (CT99021) is a GSK-3? and GSK-3? inhibitor with IC50 of 10 nM and 6.7 nM, respectively. CHIR99201 does not exhibit cross-reactivity against cyclin-dependent kinases (CDKs) and shows a 350-fold selectivity toward GSK-3? compared to CDKs.

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