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Posaconazole

Posaconazole

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Posaconazole is an inhibitor primarily of CYP3A4, but it does not inhibit the activity of other CYP enzymes; Also an inhibitor of sterol C14? demethylase inhibitor with IC50 of 0.25 ?M. Posaconazole has a median terminal elimination half-life of 15-35 hours.

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