![Tozasertib (VX-680, MK-0457)](http://plus.labcloudinc.com/cdn/shop/products/cetuximab-chemical-structure-a2000_c65e5fd2-ce7d-411d-b849-07d010fa0d03_{width}x.gif?v=1598479967)
Tozasertib (VX-680, MK-0457)
Tozasertib (VX-680, MK-0457) is a pan-Aurora inhibitor, mostly against Aurora A with Kiapp of 0.6 nM in a cell-free assay, less potent towards Aurora B/Aurora C and 100-fold more selective for Aurora A than 55 other kinases. Phase 2.