Bisindolylmaleimide IX (Ro 31-8220 Mesylate)
Bisindolylmaleimide IX (Ro 31-8220 Mesylate) is a pan-PKC inhibitor with IC50 of 5 nM, 24 nM, 14 nM, 27 nM, and 24 nM for PKC-?, PKC-?I, PKC-?II, PKC-?, and PKC-?, respectively, and also shows potent inhibition against MAPKAP-K1b, MSK1, GSK3? and S6K1.
